Recombinant Human TRP1 / TYRP1 Protein (His tag)

  • Catalog number
    PKSH030693-20µg
  • Price
    Please ask
  • Size
    20µg
  • Synonym
    b-PROTEIN;CAS2;CATB;GP75;OCA3;TRP;TRP1;TYRP
  • Activity
    NA
  • Sequence
    Met 1- Arg 471
  • Fusion tag
    C-His
  • Accession
    P17643
  • Expressed Host
    Baculovirus-Insect Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >96 % as determined by SDS-PAGE
  • Endotoxin
    <1.0 EU per µg as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    52 kDa
  • AP Mol Mass
    55 kDa
  • Formulation
    Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
  • Background
    Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.
  • Conjugation
    histidine
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    TRP1   TYRP1   Protein   His   tag  
  • Gene symbol
    TYRP1, TRP-AGG2-5
  • Short name
    Recombinant TRP1 / TYRP1 Protein (His tag)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    His
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens TRP1 / TYRP1 Protein (histidine detection labelled)
  • Alternative technique
    rec
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    tRNA-Pro (anticodon AGG) 2-5
  • Synonyms gene
  • Synonyms gene name
    • tRNA proline 1
    • tRNA proline 1 (anticodon AGG)
    • transfer RNA proline 1 (anticodon AGG)
    • transfer RNA-Pro (AGG) 2-3
    • transfer RNA-Pro (AGG) 2-5
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1989-06-30
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Cytoplasmic transfer RNAs
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee