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Anti-GNA11 (Polyclonal), ALEXA Fluor 594

Anti-GNA11 (Polyclonal), ALEXA Fluor 594 is available 0 time from Bioss polyclonal antibodies labs

Modification No modification has been applied to this antibody
Clonality Polyclonal Antibody
Other name Anti-GNA11 Polyclonal
Host organism Rabbit (Oryctolagus cuniculus)
Background information Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Ga subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gq class includes G alpha 15, G alpha 14, G alpha 11 and G alpha q, two of which, G alpha 11 and G alphaq, are abundant in brain and lung and present at lower levels in a variety of tissues (6).
Also known as GNA11 Polyclonal Antibody
Swiss Prot N/A
Specificity This antibody reacts specifically with GNA11
Modification site None
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Conjugated with ALEXA FLUOR® 594
Gene ID 2767
Clone Polyclonal Antibodies
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Synonyms G alpha-11; G-protein subunit alpha-11; GNA11; GNA11_HUMAN; Guanine nucleotide-binding protein Gy subunit alpha; Guanine nucleotide-binding protein subunit alpha-11.
Applications IF(IHC-P)
Subcellular locations N/A
Concentration 1ug per 1ul
Purification method Purified by Protein A.
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Type Conjugated Primary Antibody
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Excitation emission 590nm/617nm
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target Protein/Peptide GNA11
Antigen Source KLH conjugated synthetic peptide derived from human GNA11
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetGNA11
Short name Anti-GNA11 (Polyclonal)
Technique Polyclonal, anti
Label ALEXA FLUOR 594
Alternative name antibody to-GNA11 (polyclonal), ALEXA Fluor 594
Alternative technique polyclonals
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