KLRC3, human recombinant
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Catalog number7354-100
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PricePlease ask
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Size100 ug
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SynonymsKiller cell lectin-like receptor subfamily C, NKG2-E; NKG2E
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Alternative_namesKiller cell lectin-like receptor subfamily C, NKG2-E; NKG2E
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DescriptionPlays a role as a receptor for the recognition of MHC class I HLA-E molecules
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥90%
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AssaySDS-PAGE
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Molecular Weight19 kDa (171 aa, 94-240 aa + His Tag), confirmed by MALDI-TOF.
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Storage Temp-80°C
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ShippingDry Ice
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Shelf Life12 months
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Concentration1 mg/ml
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AppearanceLiquid
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Physical form description1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M NaCl and 10% glycerol.
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Background InformationKLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Recombinant human KLRC3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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Amino acid sequenceMGSSHHHHHH SSGLVPRGSH MGSM IPFLEQ NNSSPNTRTQ KARPCGHCPE EWITYSNSCY YIGKERRTWE ESLQACASKN SSSLLSIDNE EEMKFLASIL PSSWIGVFRN SSHHPWVTIN GLAFKHEIKD SDHAERNCAM LHVRGLISDQ CGSSRIIRRG FIMLTRLVLN S
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolKLRC3
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Short nameKLRC3, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative namekiller cellular lectin-like receptor subfamily C, member 3, H. sapiens Rec.
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Alternative techniquerec
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Alternative to gene targetkiller cell lectin-like receptor subfamily C, member 3, NKG2-E and NKG2E, KLRC3 and IDBG-18940 and ENSG00000205810 and 3823, carbohydrate binding, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene namekiller cell lectin like receptor C3
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Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-01-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-type lectin domain containing
- Killer cell lectin like receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data