Human CellExp™ LAMP1/CD107a, human recombinant

• Catalog number
  7381-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  LAMP1, CD107a
• Alternative_names
  LAMP1, CD107a
• Description
  A glycoprotein which provides selectins with carbohydrate ligands
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Biological activity
  Measured by its binding ability in a functional ELISA. When rhLAMP1 /CD107a is coated at 1 µg/ml, rhGalectin‑3 (Cat # 4684) binds with an apparent Kd
• Results
  Measured by its binding ability in a functional ELISA. When rhLAMP1 /CD107a is coated at 1 µg/ml, rhGalectin‑3 (Cat # 4684) binds with an apparent Kd
• Molecular Weight
  This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 39.2 kDa. The predicted N-terminus is Ala 29. DTT-reduced Protein migrates as 60-100 kDa due to different glycosylation.
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
• Background Information
  Lysosomal-associated membrane protein 1 (LAMP1) is also known as CD107a (Cluster of Differentiation 107a). LAMP1 / CD107a belongs to the LAMP family. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   LAMP1/CD107a  
• Gene symbol
  LAMP1
• Short name
  CellExp™ LAMP1/CD107a, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ LAMP1/CD107a, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6499
• Gene
  LAMP1
• Long gene name
  lysosomal associated membrane protein 1
• Synonyms gene name
  • lysosomal-associated membrane protein 1
• Synonyms
  • CD107a
• GenBank acession
  • J03263
• Locus
  13q34
• Discovery year
  1990-07-15
• Entrez gene record
  3916
• Classification
  • Lysosome associated membrane proteins
  • CD molecules
• VEGA ID
  OTTHUMG00000017380

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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