SMAD1 Antibody, Biotin Conjugated

• Catalog number
  bs-16376R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  SMAD1 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SMAD1
• Specificity
  This is a highly specific antibody against SMAD1. This antibody may cross react with AKAP6 due to a few animo acid sequence similarity.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  185-220/465
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human SMAD1
• Gene ID number
  4086
• Swiss Prot
  Q15797
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  SMAD1   Conjugated  
• Gene symbol
  SMAD1-AS2, SMAD1-AS1, SMAD1, GARS1
• Short name
  Anti-SMAD1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-SMAD1 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  SMAD family member 1, BSP-1 and BSP1 and JV4-1 and JV41 and MADH1 and MADR1, SMAD1 and IDBG-39936 and ENSG00000170365 and 4086, transforming growth factor beta receptor, nuclei, Smad1 and IDBG-170516 and ENSMUSG00000031681 and 17125, SMAD1 and IDBG-629431 and ENSBTAG00000002835 and 540488

Gene info

• Identity
  HGNC:49381
• Gene
  SMAD1-AS2
• Long gene name
  SMAD1 antisense RNA 2
• GenBank acession
  • BC042377
• Locus
  4q31.21
• Discovery year
  2013-10-22
• Entrez gene record
  101927659
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162185

Gene info

• Identity
  HGNC:49379
• Gene
  SMAD1-AS1
• Long gene name
  SMAD1 antisense RNA 1
• Synonyms
  • ENST00000513542
• GenBank acession
  • AW087665
• Locus
  4q31.21
• Discovery year
  2013-10-22
• Pubmed identfication
  • 24147006
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162186

Gene info

• Identity
  HGNC:6767
• Gene
  SMAD1
• Long gene name
  SMAD family member 1
• Synonyms gene
  • MADH1
• Synonyms gene name
  • MAD, mothers against decapentaplegic homolog 1 (Drosophila)
  • SMAD, mothers against DPP homolog 1 (Drosophila)
• Synonyms
  • MADR1
  • JV4-1
• GenBank acession
  • U59423
• Locus
  4q31.21
• Discovery year
  1996-11-15
• Entrez gene record
  4086
• Pubmed identfication
  • 8653785
  • 8673135
• RefSeq identity
  • NM_005900
• Classification
  • SMAD family
• VEGA ID
  OTTHUMG00000161592

Gene info

• Identity
  HGNC:4162
• Gene
  GARS1
• Long gene name
  glycyl-tRNA synthetase 1
• Synonyms gene
  • CMT2D
  • GARS
• Synonyms gene name
  • Charcot-Marie-Tooth neuropathy 2D
  • glycyl-tRNA synthetase
• Synonyms
  • GlyRS
  • DSMAV
  • SMAD1
• Synonyms name
  • glycine tRNA ligase
• GenBank acession
  • AK074524
• Locus
  7p14.3
• Discovery year
  1995-03-21
• Entrez gene record
  2617
• Pubmed identfication
  • 8595897
  • 8872480
• RefSeq identity
  • NM_002047
• Classification
  • Aminoacyl tRNA synthetases, Class II
• VEGA ID
  OTTHUMG00000152769
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
  • LRG_243

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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