CDC42 (Ser71) Antibody, ALEXA FLUOR 555

• Catalog number
  bs-3369R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  CDC42 (Ser71) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-CDC42 Ser71 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CDC42 Ser71
• Specificity
  This is a highly specific antibody against CDC42 Ser71.
• Modification
  Phosphorylation
• Modification Site
  Ser71
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human CDC42 around the phosphorylation site of Ser71
• Gene ID Number
  998
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  CDC 42; CDC42Hs; Cell division control protein 42 homolog; Cell division cycle 42; Cell division cycle 42 isoform 1; Cell division cycle 42 isoform 2; dJ224A6.1.1; dJ224A6.1.2; G25K; G25K GTP binding protein; Growth regulating protein; GTP binding protein 25kD; Small GTP binding protein CDC42.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  CDC42   Ser71  
• Gene symbol
  CDC42-AS1, CDC42-IT1, CDC42
• Short name
  Anti-CDC42 Ser71
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  CDC42 (Ser71) Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies
• Alternative to gene target
  cell division cycle 42 (GTP binding protein, 25kDa), CDC42Hs and G25K, CDC42 and IDBG-93614 and ENSG00000070831 and 998, identical protein binding, Cell surfaces, Cdc42 and IDBG-198471 and ENSMUSG00000006699 and 12540, BT.56113 and IDBG-645532 and ENSBTAG00000001700 and 532712

Gene info

• Identity
  HGNC:54314
• Gene
  CDC42-AS1
• Long gene name
  CDC42 antisense RNA 1
• Locus
  1p36.12
• Discovery year
  2019-05-03
• Entrez gene record
  112268223
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:41317
• Gene
  CDC42-IT1
• Long gene name
  CDC42 intronic transcript 1
• Synonyms gene name
  • CDC42 intronic transcript 1 (non-protein coding)
• Locus
  1p36.12
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000002890

Gene info

• Identity
  HGNC:1736
• Gene
  CDC42
• Long gene name
  cell division cycle 42
• Synonyms gene name
  • cell division cycle 42 (GTP-binding protein, 25kD)
  • cell division cycle 42 (GTP binding protein, 25kDa)
• Synonyms
  • G25K
  • CDC42Hs
• Synonyms name
  • GTP binding protein, 25kDa
• GenBank acession
  • BC018266
• Locus
  1p36.12
• Discovery year
  1991-06-06
• Entrez gene record
  998
• Pubmed identfication
  • 2124704
  • 2122236
• RefSeq identity
  • NM_001791
• Classification
  • Rho family GTPases
• VEGA ID
  OTTHUMG00000002753
• Locus Specific Databases
  • LRG_1326

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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