Biotin-Linked Polyclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 2 (TREM2)

• Catalog number
  MBS2078436
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Conjugation
  Biotinylated
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Linked   Triggering   Receptor   Expressed   Myeloid   Cells   TREM2  
• Gene symbol
  TREM2
• Short name
  -Linked Polyclonal Antibody Triggering Receptor Expressed On Myeloid Cells 2 (TREM2)
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Biotin
• Alternative name
  biotinilated-Linked polyclonal (antibody to-) to Triggering Receptor Expressed On Myeloid Cells 2 (triggering receptor expressed on myeloid cells 2)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  triggering receptor expressed on myeloid cells 2, TREM2 and IDBG-86566 and ENSG00000095970 and 54209, scaffold protein binding, Extracellular, Trem2 and IDBG-189871 and ENSMUSG00000023992 and 83433, TREM2 and IDBG-630863 and ENSBTAG00000007275 and 506467
• Tissue
  cells

Gene info

• Identity
  HGNC:17761
• Gene
  TREM2
• Long gene name
  triggering receptor expressed on myeloid cells 2
• Synonyms gene name
  • triggering receptor expressed on myeloid cells 2a
• Synonyms
  • TREM-2
  • Trem2a
  • Trem2b
  • Trem2c
• GenBank acession
  • AF213457
• Locus
  6p21.1
• Discovery year
  2002-08-09
• Entrez gene record
  54209
• Pubmed identfication
  • 10799849
  • 12080485
• RefSeq identity
  • NM_018965
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000014671
• Locus Specific Databases
  • LRG_631

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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