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Acalabrutinib for cell activation

Acalabrutinib for cell activation is available 2 times from Biovision labs

B1193-5 | Acalabrutinib for cell activation size: 5 mg | 172.29 USD

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B1193-25 | Acalabrutinib for cell activation size: 25 mg | 515.75 USD

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Other name (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; ACP-196
Supplied with N/A
Description Acalabrutinib (ACP-196) is an orally available, selective irreversible inhibitor of Bruton’s tyrosine kinase (BTK) with potential antineoplastic activity. It is a second generation BTK inhibitor with improved pharmacological properties with better plasma exposure, oral absorption and shorter half-life. It prevents the activation of B-cell antigen receptor (BCR) signaling pathway, thus preventing B-cell activation and BTK mediated activation of downstream survival pathways.
Category Biochemicals
Molecular formula C₂₆H₂₃N₇O₂
Is it cell-permeable? Yes
Molecular weight 465.52
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 1420477-60-6
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Yellow Solid
Reconstitute instructions DMSO
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Acalabrutinib for activation
Technique activation
Alternative name Acalabrutinib to measure cellular activation
Tissue cell
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