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Acalabrutinib for cell activation

Acalabrutinib for cell activation is available 2 times from Biovision labs

B1193-5 | Acalabrutinib for cell activation size: 5 mg | 172.92 USD

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B1193-25 | Acalabrutinib for cell activation size: 25 mg | 517.63 USD

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Description Acalabrutinib (ACP-196) is an orally available, selective irreversible inhibitor of Bruton’s tyrosine kinase (BTK) with potential antineoplastic activity. It is a second generation BTK inhibitor with improved pharmacological properties with better plasma exposure, oral absorption and shorter half-life. It prevents the activation of B-cell antigen receptor (BCR) signaling pathway, thus preventing B-cell activation and BTK mediated activation of downstream survival pathways.
Peptide sequence N/A
CAS number 1420477-60-6
Molecular weight 465.52
Category Biochemicals
Other name (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; ACP-196
Molecular formula C₂₆H₂₃N₇O₂ 
Physical appearance Yellow Solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetAcalabrutinib for activation
Short name Acalabrutinib for activation
Technique activation
Alternative name Acalabrutinib to measure cellular activation
Tissue cell
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