Mouse Monoclonal [clone 1G3] (IgG2b,k) to Human FGF Receptor / FGFR2

• Catalog number
  MBS245769
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [FGF Receptor / FGFR2]
• Products_name_syn
  [Anti-FGF Receptor / FGFR2 Antibody (clone 1G3) IHC-plus; FGFR2; BEK; BBDS; Bacteria-expressed kinase; CD332 antigen; CFD1; Craniofacial dysostosis 1; CEK3; Fgf bek; FGF receptor; Hydroxyaryl-protein kinase; Jackson-Weiss syndrome; JWS; FGF Receptor 2; KSAM; KGFR; Soluble FGFR4 variant 4; BFR-1; TK14; TK25; Human FGF Receptor; FGFR2]
• Other_names
  [fibroblast growth factor receptor 2 isoform 1; Fibroblast growth factor receptor 2; fibroblast growth factor receptor 2; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14; fibroblast growth factor receptor 2; K-sam; KGFR; Keratinocyte growth factor receptor; CD_antigen: CD332]
• Products_gene_name
  [FGFR2]
• Other_gene_names
  [FGFR2; FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; BEK; KGFR; KSAM; FGFR-2; KGFR]
• Clonality
  Monoclonal
• Clone
  [1G3]
• Reactivity
  Human
• Specificity
  Human FGFR2
• Purity
  Protein A Purified
• Form
  PBS, pH 7.4
• Concentration
  1 mg/ml
• Storage_stability
  Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
• Tested_application
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Monoclonal   1G3]   IgG2b   FGF   Receptor   FGFR2  
• Gene symbol
  FGF18, FGF17, NUDT6, FGFR2, FGF4, FGF1
• Short name
  Mouse Monoclonal [clone 1G3] (IgG2b k) FGF Receptor / FGFR2
• Technique
  Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2b,k, IgG2b
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse monoclonal [clonality 1G3] (IgG2b,k) to H. sapiens FGF Receptor / FGFR2
• Alternative technique
  murine
• Clone name
  1G3

Gene info

• Identity
  HGNC:3674
• Gene
  FGF18
• Long gene name
  fibroblast growth factor 18
• Synonyms
  • FGF-18
  • ZFGF5
• GenBank acession
  • AB007422
• Locus
  5q35.1
• Discovery year
  1998-12-22
• Entrez gene record
  8817
• Pubmed identfication
  • 9660775
  • 9742123
• RefSeq identity
  • NM_033649
  • NM_003862
• Classification
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000130464

Gene info

• Identity
  HGNC:3673
• Gene
  FGF17
• Long gene name
  fibroblast growth factor 17
• Synonyms
  • FGF-13
• GenBank acession
  • AB009249
• Locus
  8p21.3
• Discovery year
  1998-12-22
• Entrez gene record
  8822
• Pubmed identfication
  • 9514906
  • 9751161
• RefSeq identity
  • NM_003867
• Classification
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000097051

Gene info

• Identity
  HGNC:8053
• Gene
  NUDT6
• Long gene name
  nudix hydrolase 6
• Synonyms gene name
  • nudix (nucleoside diphosphate linked moiety X)-type motif 6
• Synonyms
  • gfg-1
  • gfg
  • FGF2AS
  • FGF-AS
• GenBank acession
  • AF019632
• Locus
  4q28.1
• Discovery year
  1999-09-03
• Entrez gene record
  11162
• Pubmed identfication
  • 7984147
  • 10022609
• RefSeq identity
  • NM_007083
• Classification
  • Nudix hydrolase family
• VEGA ID
  OTTHUMG00000039507

Gene info

• Identity
  HGNC:3689
• Gene
  FGFR2
• Long gene name
  fibroblast growth factor receptor 2
• Synonyms gene
  • KGFR
  • BEK
  • CFD1
  • JWS
• Synonyms gene name
  • bacteria-expressed kinase
  • keratinocyte growth factor receptor
  • craniofacial dysostosis 1
  • Jackson-Weiss syndrome
• Synonyms
  • CEK3
  • TK14
  • TK25
  • ECT1
  • K-SAM
  • CD332
• Synonyms name
  • Crouzon syndrome
  • Pfeiffer syndrome
• GenBank acession
  • AK026508
• Locus
  10q26.13
• Discovery year
  1991-05-09
• Entrez gene record
  2263
• RefSeq identity
  • NM_022976
  • NM_000141
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
• VEGA ID
  OTTHUMG00000019175
• Locus Specific Databases
  • LRG_994

Gene info

• Identity
  HGNC:3682
• Gene
  FGF4
• Long gene name
  fibroblast growth factor 4
• Synonyms gene
  • HSTF1
• Synonyms gene name
  • heparin secretory transforming protein 1
• Synonyms
  • K-FGF
  • HBGF-4
  • HST
  • HST-1
  • KFGF
• Synonyms name
  • human stomach cancer, transforming factor from FGF-related oncogene
  • kaposi sarcoma oncogene
  • transforming protein KS3
• GenBank acession
  • M17446
• Locus
  11q13.3
• Discovery year
  1988-04-20
• Entrez gene record
  2249
• Pubmed identfication
  • 1611909
• RefSeq identity
  • NM_002007
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000167887

Gene info

• Identity
  HGNC:3665
• Gene
  FGF1
• Long gene name
  fibroblast growth factor 1
• Synonyms gene
  • FGFA
• Synonyms gene name
  • fibroblast growth factor 1 (acidic)
• Synonyms
  • AFGF
  • ECGF
  • ECGFA
  • ECGFB
  • HBGF1
  • ECGF-beta
  • FGF-alpha
  • GLIO703
• Synonyms name
  • heparin-binding growth factor 1
  • endothelial cell growth factor, alpha
  • endothelial cell growth factor, beta
• GenBank acession
  • X59065
• Locus
  5q31.3
• Discovery year
  1986-01-01
• Entrez gene record
  2246
• Pubmed identfication
  • 1697263
  • 3523756
• RefSeq identity
  • NM_000800
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000059703

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