anti-SCF Antibody
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Catalog number79-769
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PricePlease ask
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Size0.1 mg
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Gene infoLigand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol-1, 4, 5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.
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Gene namesSF, MGF, SCF, FPH2, KL-1, Kitl, SHEP7, BCR1, D22S11, SF
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Antibodie s labelunlabelled serum
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PurityAntibodies were purified by affinity-chromatography using epitope-specific peptide.
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Ab raised inRabbit
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TypePolyclonal
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Spicific toThis antibody detects endogenous level of total SCF protein.
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AntigenSCF antibody was made against a peptide sequence around aa.265~269 (E-K-E-R-E) derived from Human SCF.
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Immuno applicationWestern Blot
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Antibody adviceWestern Blot: 1:500~1:1000
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Suspention pH azideAntibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Keep atStore antibody at -20 grades C for up to one year.
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Works withHuman
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Omim nr4505175
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Ncbi nrNP_000890.1
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KDa25 - 38 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr4254
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GENE symbolKITLG
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Antigene nameKIT ligand
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SourceHomo sapiens
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Protein nrP21583
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolKITLG
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Short nameanti-SCF Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toSCF (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameKIT ligand
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-06-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data