SARM1 Antibody, ALEXA FLUOR 488
-
Catalog number
bs-9001R-A488
-
Price
Please ask
-
Size
100ul
-
-
Long name
SARM1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known as
Anti-SARM1 PAb ALEXA FLUOR 488
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 488
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
SARM1
-
Specificity
This is a highly specific antibody against SARM1.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen range
340-380/724
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SARM1
-
Gene ID Number
23098
-
Swiss Prot
Q6SZW1
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
499nm/519nm
-
Synonyms
SARM; SAMD2; MyD88-5; Sterile alpha and TIR motif-containing protein 1; Sterile alpha and Armadillo repeat protein; Sterile alpha motif domain-containing protein 2; SAM domain-containing protein 2; Tir-1 homolog; SARM1; KIAA0524
-
Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-SARM1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor
-
French translation
anticorps
-
Gene target
-
Gene symbol
SARM1
-
Short name
Anti-SARM1
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 488
-
Alternative name
SARM1 Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative technique
antibodies
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products