Human CellExp™ Activin A, Human Recombinant

• Catalog number
  6442-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Human Cellexp Human Recombinant Activin A
• Alternative_names
  Inhba, Inhibin beta A, FSH releasing protein, FRP
• Description
  A protein complex enhancing FSH biosynthesis and secretion
• Recombinant
  Yes
• Source
  Human cell expressed
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 ug of protein
• Biological activity
  ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line).
• Results
  0.5 to 5 ng/ml
• Molecular Weight
  25 kDa, homodimer, nonglycosylated.
• Storage Temp
  -20°C
• Shipping
  gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from a PBS solution.
• Reconstitution Instructions
  Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
• Background Information
  Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-β super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision’s Activin A is produced in a serum-free, chemically defined media.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   Activin  
• Short name
  CellExp™ Activin A, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ Activin A, H. sapiens Rec.
• Alternative technique
  rec

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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