Recombinant Mouse Syndecan-4 / SDC4 Protein (Fc tag) 100µg

• Catalog number
  PKSM040519-100µg
• Price
  Please ask
• Size
  100µg

• Activity
  Measured by its binding ability in a functional ELISA. Immobilized human MDK at 10 μg/ml (100 μl/well) can bind mouse SDC4-Fc with a linear range of 0.16-1.25 μg/ml.
• Synonym
  AA959608;AW108331;ryudocan;Synd4;syndecan-4
• Sequence
  Met1-Val146
• Fusion tag
  C-Fc
• Accession
  O35988
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 95 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  40.5 kDa
• AP Mol Mass
  33 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty.
• Technical data
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Syndecan-4   SDC4   Protein   tag   100µg  
• Gene symbol
  SDC4
• Short name
  Recombinant Mouse Syndecan-4 / SDC4 Protein (Fc tag) 100µg
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  Fc Tag
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Syndecan-4 / syndecan 4 Protein (fragment c detection labelled) 100µg
• Alternative technique
  rec, murine
• Alternative to gene target
  syndecan 4, SYND4, SDC4 and IDBG-77503 and ENSG00000124145 and 6385, thrombospondin receptor activity, Cell surfaces, Sdc4 and IDBG-212144 and ENSMUSG00000017009 and 20971, SDC4 and IDBG-642873 and ENSBTAG00000015127 and 508133

Gene info

• Identity
  HGNC:10661
• Gene
  SDC4
• Long gene name
  syndecan 4
• Synonyms gene name
  • syndecan 4 (amphiglycan, ryudocan)
• Synonyms
  • SYND4
  • amphiglycan
  • ryudocan
• Synonyms name
  • syndecan proteoglycan 4
• GenBank acession
  • X67016
  • D13292
• Locus
  20q13.12
• Discovery year
  1994-05-17
• Entrez gene record
  6385
• Pubmed identfication
  • 7916598
  • 1500433
• RefSeq identity
  • NM_002999
• Classification
  • Syndecans
• VEGA ID
  OTTHUMG00000033083

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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