Recombinant Human P63 / TP63 / Tumor protein p63 Protein (His & GST tag) 100µg

• Catalog number
  PKSH030689-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  AIS;B(p51A);B(p51B);EEC3;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP73L
• Activity
  NA
• Sequence
  Met 1-Glu 680
• Fusion tag
  N-His & GST
• Accession
  Q9H3D4-1
• Expressed Host
  Baculovirus-Insect Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞90 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  105 kDa
• AP Mol Mass
  125 kDa
• Formulation
  Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 0.3mM DTT, 20% glycerol
• Reconstitution
  Please refer to it for detailed information.
• Background
  Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar features in their gene structures and functions. An animal model, p63-/- mice has been useful in difining the role p63 plays in the development and maintenance of stratified epithelial tissues. This p63 encoding protein p63 has a dramatic impact on replenishment of cutaneous epithelial stem cells and on ovarian germ cell survival. Although these two fundamental roles of p63 attest to its powerful place in development, its other functions, specifically the apparent capacity of p63, is to supervise the emergence of new cell populations in the breast, prostate, cervix, and upper reproductive tract. P63-/- mice have several development defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this protein are associated with ectodermal dysplasia, and cleft lip / palate syndrome 3, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, et al.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  P63   TP63   Tumor   protein   p63   Protein   His   GST   tag   100µg  
• Gene symbol
  MGST3, TP63, CKAP4
• Short name
  Recombinant P63 / TP63 / Tumor protein p63 Protein (His & GST tag) 100µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens P63 / tumor protein p63 / Tumor protein p63 Protein (histidine & GST detection labelled) 100µg
• Alternative technique
  rec
• Alternative to gene target
  tumor protein p63, AIS and B(p51A) and B(p51B) and EEC3 and KET and LMS and NBP and OFC8 and p40 and p51 and p53CP and p63 and p73H and p73L and RHS and SHFM4 and TP53CP and TP53L and TP73L, TP63 and IDBG-69487 and ENSG00000073282 and 8626, WW domain binding, nuclei, Trp63 and IDBG-150133 and ENSMUSG00000022510 and 22061, TP63 and IDBG-634533 and ENSBTAG00000015460 and 615335
• Tissue
  tumor

Gene info

• Identity
  HGNC:7064
• Gene
  MGST3
• Long gene name
  microsomal glutathione S-transferase 3
• Synonyms
  • GST-III
• Synonyms name
  • microsomal glutathione S-transferase III
  • microsomal GST-3
  • microsomal GST-III
• GenBank acession
  • AF026977
• Locus
  1q24.1
• Discovery year
  1997-10-16
• Entrez gene record
  4259
• Pubmed identfication
  • 9278457
• RefSeq identity
  • NM_004528
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000034627

Gene info

• Identity
  HGNC:15979
• Gene
  TP63
• Long gene name
  tumor protein p63
• Synonyms gene
  • TP73L
  • TP53L
  • TP53CP
• Synonyms gene name
  • tumor protein p73-like
  • tumor protein p53-like
  • tumor protein p53-competing protein
• Synonyms
  • p51
  • SHFM4
  • EEC3
  • p63
  • p73L
  • OFC8
  • KET
  • p73H
  • NBP
  • p53CP
• GenBank acession
  • AB010153
• Locus
  3q28
• Discovery year
  2002-04-18
• Entrez gene record
  8626
• Pubmed identfication
  • 9774969
  • 9662378
  • 11181441
  • 11181451
• RefSeq identity
  • NM_003722
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000156313
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_428

Gene info

• Identity
  HGNC:16991
• Gene
  CKAP4
• Long gene name
  cytoskeleton associated protein 4
• Synonyms gene name
  • cytoskeleton-associated protein 4
• Synonyms
  • P63
  • CLIMP-63
  • ERGIC-63
• GenBank acession
  • X69910
• Locus
  12q23.3
• Discovery year
  2001-11-14
• Entrez gene record
  10970
• Pubmed identfication
  • 8314870
• VEGA ID
  OTTHUMG00000170085

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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