ApoER2 (LRP8) Antibody (CT)
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Catalog number
6721-100
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Price
Please ask
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Size
100 μl
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Antibody Target
ApoER2
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Target Alternative Name
LRP8; APOER2; Low-density lipoprotein receptor-related protein 8; Apolipoprotein E receptor 2
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Antibody Type
Polyclonal
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Species Reactivities
Human
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Immunogen Sequence
This APOER2 (LRP8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-963 amino acids from the C-terminal region of human APOER2 (LRP8).
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Accession
Q14114
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Gene Id
7804
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
100 µl of antibody in PBS with 0.09% (W/V) sodium azide
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Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Application
Western blot, IHC
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Positive Control
Western blot: Placenta lysate, IHC: human cancer tissue
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Application And Usages
Western blot: ~1:1000, IHC: ~1:50-1:100.
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Description
ApoER2 (apolipoprotein E receptor 2), also designated LRP8, is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. ApoER2 is expressed in brain and placenta and has several splice variants. ApoER2 is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
LRP8-DT, LRP8
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Short name
ApoER2 (LRP8) Antibody (CT)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
ApoER2 (low density lipoprotein receptor-related protein 8, apolipoprotein e receptor) (antibody to-) (CT)
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Alternative technique
antibodies
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Alternative to gene target
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, APOER2 and HSZ75190 and LRP-8 and MCI1, LRP8 and IDBG-98740 and ENSG00000157193 and 7804, reelin receptor activity, Extracellular, Lrp8 and IDBG-171850 and ENSMUSG00000028613 and 16975, LRP8 and IDBG-639215 and ENSBTAG00000000736 and
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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