Recombinant Human Tissue Inhibitor of Metalloproteinases 4/TIMP-4 (C-6His)

• Catalog number
  CJ60
• Price
  Please ask
• Size
  1mg

• Alternative names
  Metalloproteinase inhibitor 4,TIMP-4,Tissue inhibitor of metalloproteinases 4,TIMP4
• Description
  Recombinant Human Tissue Inhibitor of Metalloproteinases 4 is produced by our Mammalian expression system and the target gene encoding Cys30-Pro224 is expressed with a 6His tag at the C-terminus.
• Expression
  Human Cells
• Tag
  C-His
• Endotoxin
  Less than 0.1 ng/ug (1 EU/ug)
• Accession
  Q99727
• TargetSequence
  Cys30-Pro224
• Shipping
  Ambient
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
• Note
  For research use only.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. 6
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tissue   Inhibitor   Metalloproteinases   4/TIMP-4   C-6His  
• Gene symbol
  TIMP4, TIMP1, MIR1302-4, PIRC18, PIRC16, SNORD114-4, IGKV2OR2-4, MIR941-4
• Short name
  Recombinant Tissue Inhibitor of Metalloproteinases 4/TIMP-4 (C-6His)
• Technique
  Recombinant, tissue, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture. tissues
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Tissue suppressor on Metalloproteinases 4/TIMP-4 (C-6His)
• Alternative technique
  rec, tissues
• Tissue
  tissue

Gene info

• Identity
  HGNC:11823
• Gene
  TIMP4
• Long gene name
  TIMP metallopeptidase inhibitor 4
• Synonyms gene name
  • tissue inhibitor of metalloproteinase 4
• GenBank acession
  • U76456
• Locus
  3p25.2
• Discovery year
  1997-07-07
• Entrez gene record
  7079
• Pubmed identfication
  • 8939999
  • 9693046
• RefSeq identity
  • NM_003256
• Classification
  • Tissue inhibitor of metallopeptidases
• VEGA ID
  OTTHUMG00000129763

Gene info

• Identity
  HGNC:11820
• Gene
  TIMP1
• Long gene name
  TIMP metallopeptidase inhibitor 1
• Synonyms gene
  • TIMP
  • CLGI
• Synonyms gene name
  • tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
• Synonyms
  • EPO
• Locus
  Xp11.3
• Discovery year
  1986-01-01
• Entrez gene record
  7076
• RefSeq identity
  • NM_003254
• Classification
  • Tissue inhibitor of metallopeptidases
• VEGA ID
  OTTHUMG00000021447
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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