anti-RAF1 Antibody

• Catalog number
  48-711
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  RAF, a member of the Raf Subfamily of Serine/Threonine Protein Kinases, is part of the RAS-dependent signalling pathway. Once activated, Raf-1 can activate the dual specificity protein kinases MEK1 and MEK2 which in turn activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. t(3;8)(p25;q21) translocations involving RAF1 result in mixed parotid gland tumors. Raf1 is an ocogene that has been reported to be overexpressed in many tumor types.
• Gene names
  RAF1, C-Raf, C-raf-1, CRAF, NS5, Raf-1, Proto-oncogene c-RAF, Oncogene RAF1, RAF, Raf1 kinase
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  pSer259
• Antigen
  RAF1 antibody was made against amino acids surrounding Ser 259 of RAF1 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  RAF1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200.
• Suspention pH azide
  PBS, 0.02% sodium azide, 50% glycerol.
• Keep at
  RAF1 antibody should be stored long term (months) at -80 grades C and short term (days) at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  125651
• Ncbi nr
  P04049
• Vial with antibody
  in solution
• NCBI GENE nr
  5894
• GENE symbol
  RAF1
• Antigene name
  v-raf-1 murine leukemia viral oncogene homolog 1
• Source
  Homo sapiens
• Protein nr
  P04049
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RAF1  
• Gene symbol
  RNASE3, RAF1
• Short name
  anti-RAF1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toRAF1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  v-raf-1 murine leukemia viral oncogene homolog 1, c-Raf and CMD1NN and CRAF and NS5 and Raf-1, RAF1 and IDBG-19277 and ENSG00000132155 and 102724915,5894, transferase activity, nuclei, Raf1 and IDBG-179428 and ENSMUSG00000000441 and 110157, RAF1 and IDBG-646381 and ENSBTAG00000004514 and 521196

Gene info

• Identity
  HGNC:10046
• Gene
  RNASE3
• Long gene name
  ribonuclease A family member 3
• Synonyms gene
  • RNS3
• Synonyms gene name
  • ribonuclease, RNase A family, 3
• Synonyms
  • ECP
  • RAF1
• Synonyms name
  • eosinophil cationic protein
• GenBank acession
  • X55990
• Locus
  14q11.2
• Discovery year
  1990-02-24
• Entrez gene record
  6037
• Pubmed identfication
  • 1577491
• RefSeq identity
  • NM_002935
• Classification
  • Ribonuclease A family
• VEGA ID
  OTTHUMG00000029604

Gene info

• Identity
  HGNC:9829
• Gene
  RAF1
• Long gene name
  Raf-1 proto-oncogene, serine/threonine kinase
• Synonyms gene name
  • v-raf-1 murine leukemia viral oncogene homolog 1
• Synonyms
  • Raf-1
  • c-Raf
  • CRAF
• Synonyms name
  • C-Raf proto-oncogene, serine/threonine kinase
• GenBank acession
  • X03484
• Locus
  3p25.2
• Discovery year
  1986-01-01
• Entrez gene record
  5894
• Pubmed identfication
  • 1611909
• RefSeq identity
  • NM_002880
• Classification
  • Mitogen-activated protein kinase kinase kinases
  • RAF family
• VEGA ID
  OTTHUMG00000129789
• Locus Specific Databases
  • LRG_413

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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