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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
This product doesn't have CAS Number
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Chemical s molecular weight
423.4
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Chemical s main applications
Isotope labelled Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
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Chemical s category
Anti-virals, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
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Other name
(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide-d4; GSK 1349572-d4; S/GSK1349572-d4;
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Chemical s formula
C20H15D4F2N3O5
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Physical properties
Off-White to Pale Beige Solid
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Melting temperature
>160°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO, Methanol
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Stability conditions
No Data Available
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Storage
Refrigerator
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