Podocalyxin Antibody

• Catalog number
  bs-1345R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Podocalyxin Primary Polyclonal Antibody
• Also known as
  Podocalyxin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Podocalyxin
• Specificity
  This is a highly specific antibody against Podocalyxin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  526-558/558
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Podocalyxin
• Gene ID number
  5420
• Swiss Prot
  O00592
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PC; PCLP; Gp2; PCLP-1; Podocalyxin; GCTM-2 antigen; Podocalyxin-like protein 1; PODXL; PCLP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Podocalyxin  
• Gene symbol
  PODXL2, PODXL
• Short name
  Anti-Podocalyxin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Podocalyxin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17936
• Gene
  PODXL2
• Long gene name
  podocalyxin like 2
• Synonyms gene name
  • podocalyxin-like 2
• Synonyms
  • PODLX2
  • endoglycan
• Synonyms name
  • endoglycan
• GenBank acession
  • AF219137
• Locus
  3q21.3
• Discovery year
  2004-07-21
• Entrez gene record
  50512
• Pubmed identfication
  • 10722749
• RefSeq identity
  • NM_015720
• VEGA ID
  OTTHUMG00000159642

Gene info

• Identity
  HGNC:9171
• Gene
  PODXL
• Long gene name
  podocalyxin like
• Synonyms gene name
  • podocalyxin-like
• Synonyms
  • PCLP
  • Gp200
  • PC
  • PODXL1
  • PDX
  • gp135
• Locus
  7q32.3
• Discovery year
  1997-07-11
• Entrez gene record
  5420
• Pubmed identfication
  • 9339384
  • 20706633
• RefSeq identity
  • NM_001018111
• VEGA ID
  OTTHUMG00000154918

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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