BTLA Polyclonal Antibody

• Catalog number
  A1082-50
• Price
  Please ask
• Size
  50 µg

• Antibody Target
  BTLA
• Target Alternative Name
  BTLA, CD272
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Accession
  Q7Z6A9
• Gene Id
  151888
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  PBS with 0.09% (W/V) sodium azide.
• Purification
  Protein A column, followed by peptide affinity purification.
• Application
  IHC, IF, WB
• Positive Control
  WB: Jurkat cell lysate; IHC: human intestine tissue; IF; human instetine tissue
• Application And Usages
  WB: 1-2 µg/ml; IHC: 2.5 µg/ml; IF: 20 µg/ml
• Description
  The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain. Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells. Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  BTLA  
• Gene symbol
  BTLA
• Short name
  BTLA Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  B and T lymphocyte associated polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  B and T lymphocyte associated, BTLA and IDBG-49858 and ENSG00000186265 and 151888, protein binding, Cell surfaces, Btla and IDBG-162900 and ENSMUSG00000052013 and 208154, BTLA and IDBG-632288 and ENSBTAG00000011871 and 531767

Gene info

• Identity
  HGNC:21087
• Gene
  BTLA
• Long gene name
  B and T lymphocyte associated
• Synonyms
  • BTLA1
  • CD272
• GenBank acession
  • AY293286
• Locus
  3q13.2
• Discovery year
  2003-08-20
• Entrez gene record
  151888
• Pubmed identfication
  • 12796776
• RefSeq identity
  • NM_181780
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000159255

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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