DUSP12 (AF28B2) Monoclonal Antibody

• Catalog number
  bsm-50384M
• Price
  Please ask
• Size
  0.1ml

• Long name
  DUSP12 (AF28B2) Monoclonal Antibody
• Also known as
  DUSP12 (AF28B2) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DUSP12
• Specificity
  This is a highly specific antibody against DUSP12.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  AF28B2
• Source
  Recombinant human protein purified from E.coli
• Gene ID number
  11266
• Swiss Prot
  Q9UNI6
• Tested Applications
  WB
• Recommended dilutions
  WB(1:5,000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Dual specificity phosphatase(DUSP) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs can be divided into six subgroups on the basis of sequence similarity(PRLs, Cdc14 phosphatases, PTENs, myotubularins, MKPs, atypical DUSPs). DUSP inhibitors might be used to manipulate MAPK and cellular responses in both positive and negative ways. The regulated expression and activity of DUSP family members in different cells and tissues controls MAPK intensity and duration to determine the type of physiological response. DUSP12(YVH1, GKAP) contains the consensus DUSP catalytic domain as well as an extended C-terminal domain of unknown function, thought to be related to its potential role in glucokinase regulation. It is localized in the cytoplasm and nucleus.
• Purification method
  Ammonium sulfate precipitation
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  YVH1; DUSP1; Dual specificity protein phosphatase 12; Dual specificity tyrosine phosphatase YVH1; DUSP12
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  DUSP12   AF28B2   Monoclonal  
• Gene symbol
  DUSP12
• Short name
  Anti-DUSP12
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1 κ
• Alternative name
  DUSP12 (AF28B2) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3067
• Gene
  DUSP12
• Long gene name
  dual specificity phosphatase 12
• Synonyms
  • YVH1
  • DUSP1
• Synonyms name
  • serine/threonine specific protein phosphatase
  • YVH1 protein-tyrosine phosphatase (S. cerevisiae) ortholog
• GenBank acession
  • AF119226
• Locus
  1q23.3
• Discovery year
  2000-01-31
• Entrez gene record
  11266
• Pubmed identfication
  • 10446167
• RefSeq identity
  • NM_007240
• Classification
  • Atypical dual specificity phosphatases
• VEGA ID
  OTTHUMG00000034540

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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