PTH, human recombinant

• Catalog number
  4650-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Parathyrin, PTH, Parathormone
• Alternative_names
  Parathyrin, PTH, Parathormone
• Description
  A hormone regulating serum calcium
• Recombinant
  Yes
• Source
  E. coli
• Assay
  SDS-PAGE
• Purity
  ≥98%
• Biological activity
  Recombinant human PTH is fully active when compared to standards. The activity calculated by umR10⁶ cells/cAMP method corresponds to a specific activity of 1 x 10⁴ IU/mg.
• Molecular Weight
  9.0 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Sterile filtered and lyophilized powder
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
• Background Information
  Parathyroid Hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extraCellular fluid. This hormone is secreted from cells of the parathyroid glands and targets cells in bone and kidney. Like other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intraCellular processing, the mature hormone is packaged within the Golgi into secretary vesicles and secreted into blood by exocytosis. Recombinant human PTH is a 9 kDa protein consisting of 84 amino acid residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PTH  
• Gene symbol
  PTH
• Short name
  PTH, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  parathyroid hormone, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  parathyroid hormone, PTH1, PTH and IDBG-32891 and ENSG00000152266 and 5741, peptide hormone receptor binding, Extracellular, Pth and IDBG-207092 and ENSMUSG00000059077 and 19226, PTH and IDBG-632953 and ENSBTAG00000019080 and 280903

Gene info

• Identity
  HGNC:9606
• Gene
  PTH
• Long gene name
  parathyroid hormone
• Synonyms
  • PTH1
• Synonyms name
  • parathyrin
  • parathormone
  • parathyroid hormone 1
  • preproparathyroid hormone
  • prepro-PTH
• GenBank acession
  • J00301
• Locus
  11p15.3
• Discovery year
  2001-06-22
• Entrez gene record
  5741
• Pubmed identfication
  • 1672845
• RefSeq identity
  • NM_000315
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000165785

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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