CD41 / Platelet GPIIb monoclonal antibody

• Catalog number
  A7-309-T100
• Price
  Please ask
• Size
  100 assays

• Long name
  Mouse Monoclonal Antibody against Human CD41 / Platelet GPIIb, Clone: MEM-06
• Antigen
  CD41
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-06
• Applications
  FC
• Immunogen
  Leukocytes of patient suffering from LGL-type leukaemia.
• Format conjugation
  Alexa Fluor 700
• Specificity
  The antibody MEM-06 reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes. _x000D_ _x000D_ Workshop: HLDA 10
• Research area
  CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD41 / Platelet GPIIb, Clone: MEM-06 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Description
  Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures.
• French translation
  anticorps

• Gene target
  CD41   Platelet   GPIIb   monoclonal  
• Gene symbol
  ITGA2B
• Short name
  Anti-CD41 / Platelet GPIIb Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD41 / Platelet GPIIb
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6138
• Gene
  ITGA2B
• Long gene name
  integrin subunit alpha 2b
• Synonyms gene
  • GP2B
• Synonyms gene name
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
• Synonyms
  • CD41B
  • CD41
  • PPP1R93
• Synonyms name
  • protein phosphatase 1, regulatory subunit 93
  • platelet glycoprotein IIb of IIb/IIIa complex
• Locus
  17q21.31
• Discovery year
  1986-01-01
• Entrez gene record
  3674
• Classification
  • CD molecules
  • Integrin alpha subunits
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000177935
• Locus Specific Databases
  • LRG_479

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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