Thyrotrophin Receptor, aa354-359

• Catalog number
  GEN600191
• Price
  Please ask
• Size
  200ug

• Also known as
  Thyrotrophin Receptor, aa354-359
• Other names
  thyrotropin receptor; Thyrotropin receptor; thyrotropin receptor; TSH-R; thyroid-stimulating hormone receptor; thyroid stimulating hormone receptor; Thyroid-stimulating hormone receptor
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Tshr; Tshr; TSHRA; N/A
• Gene name synonims
  Tshr; Tshr; TSHRA; N/A
• Other gene names
  Tshr; Tshr; TSHRA; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  3H3043
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes both native and denatured human thyrotrophin receptor aa354-359. Reacts with the mutant thyrotrophin receptor known as I167N as well as the wild type molecule. Inhibits binding of TSH. Does not crossreact with related LH and FSH receptors. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Thyrotrophin   Receptor   aa354-359  
• Short name
  Thyrotrophin Receptor, aa354-359
• Alternative name
  Anti-Thyrotrophin Receptor, aa354-359

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