CD40 Ligand, soluble, Recombinant, Human (CD40 Ligand, CD40-L, CD40L, CD40LG, hCD40L, sCD40L, CD178, gp39, HIGM1, IGM, IMD3, T-BAM, T-cell Antigen GP39, TNF-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, TNF Ligand Su[CD40 Ligand, soluble]
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Catalog numberMBS650421
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PricePlease ask
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SizeNA
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Products_typeRecombinant Protein
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DescriptionAntigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
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SourceRecombinants or rec. proteins
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Grouprecombinants
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolCD40LG, CD40, TNF, TNFRSF1A, TNFRSF1B, LTBR, TBXT, ACP5, PLS3, FASLG
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Short nameCD40 Ligand, soluble, Recombinant, (CD40 Ligand, CD40-L, CD40L, CD40LG, hCD40L, sCD40L, CD178, gp39, HIGM1, IGM, IMD3, T-BAM, T- Antigen GP39, TNF- Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, TNF Ligand Su[CD40 Ligand, soluble]
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TechniqueRecombinant, activation, antigen, IgM, antigenes, IgMs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostHuman, recombinant (E Coli)
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IsotypeIgM, IgM
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SpeciesHuman, Humans
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Alternative nameCD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand, soluble, Rec., H. sapiens (CD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand, CD40 molecule, tumor necrosis factor receptor superfamily member 5-L, CD40L, CD40 molecule, tumor necrosis factor receptor superfamily member 5 ligand, hCD40L, sCD40L, CD178, gp39, HIGM1, Immunoglobulin M, IMD3, T-BAM, T-cellular protein GP39, tumor necrosis factor-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand supergroup Member 5, tumor necrosis factor Ligand Su[CD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand, soluble]
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Alternative techniquerec, antigenes, immunoglobulin-m
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Alternative to gene targetCD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849
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Tissuecell, tumor
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Gene info
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Identity
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Gene
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Long gene nameCD40 ligand
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameCD40 molecule
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 5
- CD40 molecule, TNF receptor superfamily member 5
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Tumor necrosis factor receptor superfamily
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameT-box transcription factor T
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Synonyms gene
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Synonyms gene name
- T, brachyury homolog (mouse)
- T brachyury transcription factor
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GenBank acession
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Locus
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Discovery year1996-04-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- T-box transcription factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameacid phosphatase 5, tartrate resistant
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-02-23
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Entrez gene record
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Pubmed identfication
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Classification
- Acid phosphatases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameplastin 3
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Synonyms gene name
- plastin 3 (T isoform)
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-08-18
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Entrez gene record
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Pubmed identfication
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Classification
- EF-hand domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameFas ligand
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 6
- Fas ligand (TNF superfamily, member 6)
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-12-09
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
- Death inducing signaling complex
- CD molecules
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VEGA ID
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Locus Specific Databases