CRIM1 Antibody (CT)

• Catalog number
  5287-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  CRIM1
• Target Alternative Name
  Cysteine rich transmembrane BMP regulator 1 (chordin-like), CRIM-1, Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  CRIM1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Crim1.
• Accession
  Q9NZV1
• Gene Id
  51232
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.
• Purification
  Affinity chromatography purified via peptide column
• Application
  Western blot, ELISA
• Positive Control
  Western Blot: Jurkat cell lysate
• Application And Usages
  Western Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.
• Description
  CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CRIM1  
• Gene symbol
  CRIM1, CRIM1-DT
• Short name
  CRIM1 Antibody (CT)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG1
• Alternative name
  CRIM1 (antibody to-) (CT)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2359
• Gene
  CRIM1
• Long gene name
  cysteine rich transmembrane BMP regulator 1
• Synonyms gene
  • S52
• Synonyms gene name
  • cysteine-rich motor neuron 1
  • cysteine rich transmembrane BMP regulator 1 (chordin-like)
• GenBank acession
  • AF168681
• Locus
  2p22.2
• Discovery year
  1999-07-22
• Entrez gene record
  51232
• Pubmed identfication
  • 10642437
• RefSeq identity
  • NM_016441
• Classification
  • Cysteine rich transmembrane BMP regulators
• VEGA ID
  OTTHUMG00000099419

Gene info

• Identity
  HGNC:54057
• Gene
  CRIM1-DT
• Long gene name
  CRIM1 divergent transcript
• Locus
  2p22.2
• Discovery year
  2018-09-27
• Entrez gene record
  100288911
• RefSeq identity
  • NR_037631
• Classification
  • Divergent transcripts

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products