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Products_type
Antibody
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Products_short_name
[APLNR/ Apelin Receptor / APJ]
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Products_name_syn
[Anti-APLNR/ Apelin Receptor / APJ Antibody (Extracellular Domain) IHC-plus; APLNR; AGTRL1; Angiotensin receptor-like 1; Angiotensin II receptor-like 1; Apelin receptor; APJ; APJ (apelin) receptor; APJR; G protein-coupled receptor APJ; HG11 orphan receptor; HG11; APJ receptor; G-protein coupled receptor APJ; Human APLNR/ Apelin Receptor; APJ]
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Other_names
[apelin receptor; Apelin receptor; apelin receptor; APJ receptor; HG11 orphan receptor; APJ (apelin) receptor; angiotensin receptor-like 1; G protein-coupled receptor APJ; G-protein coupled receptor APJ; angiotensin II receptor-like 1; G-protein coupled receptor HG11; apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11]
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Products_gene_name
[APLNR]
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Products_gene_name_syn
[APJ]
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Other_gene_names
[APLNR; APLNR; APJ; APJR; HG11; AGTRL1; AGTRL1; APJ]
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Clonality
Polyclonal
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Reactivity
Gibbon, Gorilla, Human, Monkey, Orangutan Predicted Reactivity: Horse, Rabbit (at least 90% immunogen sequence identity)
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Specificity
Human Apelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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Purity
Immunoaffinity Purified
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Form
PBS, 0.1% sodium azide.
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Concentration
1 mg/ml
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Storage_stability
Long term: -70 degree C; Short term: +4 degree C
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Tested_application
Immunohistochemistry (IHC - Paraffin)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
