MOUSE Anti-EBOLA VIRUS Antibody

  • Catalog number
    GEN214551
  • Price
    Please ask
  • Size
    200ug
  • Also known as
    EBOLA VIRUS
  • Other names
    Matrix protein VP40; Matrix protein VP40; N/A; N/A; Membrane-associated protein VP40
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    N/A; VP40; N/A; N/A
  • Gene name synonims
    N/A; VP40; N/A; N/A
  • Other gene names
    N/A; VP40; N/A; N/A
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2a
  • Clone
    FE18
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Viral; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    EBOLA VIRUS This item recognises the VP40 matrix protein of the Zaire strain of the Ebola virus, a virus that causes hemorrhagic fever. Ebola hemorrhagic fever is potentially lethal and is characterised by a wide range of symptoms including fever, vomiting, diarrhea, generalized pain or malaise, and sometimes internal and external bleeding. The cause of death is usually hypovolemic shock or organ failure. Mortality rates are extremely high, the Zaire strain of the Ebola virus is the most lethal (up to 90% mortality rate). The viruses are characterised by a long, filamentous morphology surrounded by a protein/lipid viral envelope and are transmitted by direct contact with infected blood, body fluids or tissues. VP40 promotes viral assembly and budding by interacting with host proteins of the multivesicular body pathway. It may exist as a monomer, homo-hexamer or homo-octamer.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    Purified (Purified IgG - liquid)
  • Concentration
    IgG concentration 1.0mg/ml
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
  • Tested applications
    ELISA (EIA), Western Blot (WB)
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    VIRUS  
  • Gene symbol
    EBVS1
  • Short name
    MOUSE Anti- VIRUS Antibody
  • Technique
    Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
  • Host
    mouse
  • Species
    Virus, Mouses, Viruses
  • Alternative name
    Anti-MOUSE ANTI EBOLA VIRUS
  • Alternative technique
    antibodies, murine
  • Disease
    Marburg or Ebola viruses ( EBOV ) need to be handled in BSL4 Biological safety level 4. However the monoclonal and polyclonal antibodies, ELISAs and recombinant proteins do not need any specific safety measure because no active virus is involved. The Zaire Ebola strain is called ZEBOV. The Sudan virus is called SEBOV.
Gene info
  • Identity
  • Gene
  • Long gene name
    Epstein Barr virus integration site 1
  • Synonyms gene name
    • Epstein Barr virus insertion site 1
  • GenBank acession
  • Locus
  • Discovery year
    1988-07-29
  • Entrez gene record
  • Pubmed identfication
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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