Recombinant Human Protein SCO1 Homolog Mitochondrial SCO1/SCOD1 Protein(N-GST)

  • Catalog number
    PKSH032971-10µg
  • Price
    Please ask
  • Size
    10µg
  • Synonym
    Protein SCO1 Homolog Mitochondrial; SCO1; SCOD1
  • Activity
    NA
  • Sequence
    Gly132-Ser300
  • Fusion tag
    N-GST
  • Accession
    O75880
  • Expressed Host
    E.coli
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    >95% as determined by reducing SDS-PAGE.
  • Endotoxin
    <1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
  • Mol Mass
    20.1 kDa
  • AP Mol Mass
    19 kDa
  • Formulation
    Lyophilized from a 0.2 μm filtered solution of 50mM PB, 1mM DTT, pH 7.2.
  • Background
    Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    SCO1, MGST3, GH1, POLM, NRAS, SDC3, PIGN, WASL, MAP6, HLA-N
  • Short name
    Recombinant Protein SCO1 Homolog Mitochondrial SCO1/SCOD1 Protein(N-GST)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens Protein SCO1 Homolog Mitochondrial SCO1/SCOD1 Protein(N-GST)
  • Alternative technique
    rec
  • Tissue
    mitochondrial
Gene info
  • Identity
  • Gene
  • Long gene name
    synthesis of cytochrome C oxidase 1
  • Synonyms gene
  • Synonyms gene name
    • SCO (cytochrome oxidase deficient, yeast) homolog 1
    • SCO cytochrome oxidase deficient homolog 1 (yeast)
    • SCO1, cytochrome c oxidase assembly protein
    • SCO cytochrome c oxidase assembly protein 1
  • GenBank acession
  • Locus
  • Discovery year
    1998-07-03
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Mitochondrial respiratory chain complex assembly factors
  • VEGA ID
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    DNA polymerase mu
  • Synonyms gene name
    • polymerase (DNA directed), mu
    • polymerase (DNA) mu
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    2000-02-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • DNA polymerases
    • MicroRNA protein coding host genes
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
  • Tree numbers
    • E01.370.225.812.735.830
    • E05.200.812.735.830
    • E05.478.566.380.810
    • E05.478.566.639.810
    • E05.478.594.760.830
    • E05.601.470.380.810
    • E05.601.470.639.810
  • Qualifiers
    ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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