MK-571

  • Catalog number
    2691-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    (E)-​3-​[[[3-​[2-​(7-​chloro-​2-​quinolinyl)ethenyl]phenyl][[3-​(dimethylamino)-​3-​oxopropyl]thio]methyl]thio]-​propanoic acid; L-660,711
  • Description
    MK 571 is a selective, CysLT1 receptor antagonist. It blocks the binding of leukotriene LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively. MK 571 effectively blocks LTD4 activation of recombinant human and murine CysLT1 receptors but is ineffective at blocking LTC4 or LTD4activation of the recombinant human or murine CysLT2 receptors. MK-57 also acts as a specific inhibitor of multi-drug resistance protein-1 (MRP1).
  • CAS Number
    115104-28-4
  • Structure Available
    Y
  • Salt Form
    No
  • Molecular Formula
    C₂₆H₂₇ClN₂O₃S₂
  • Molecular Weight
    515.09
  • Cell Permeable
    Yes
  • Purity
    ≥95%
  • Solubilities
    DMSO (~40 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A selective, CysLT1 receptor antagonist and multi-drug resistance protein-1 (MRP1) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • PubChem CID
    5281888
  • SMILES
    CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O
  • InChi
    InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+
  • InChi Key
    AXUZQJFHDNNPFG-UXBLZVDNSA-N
  • MSDS Available
    Yes
  • Gene target
    MK-571  
  • Gene symbol
    MVK, STYXL1, MDK, MIR571, MAPKAPK3, EPCAM
  • Short name
    MK-571
  • Alternative name
    MK-571
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Similar products
Filters
Contact
Chat with gentaur.com employee