Saracatinib (AZD0530)

  • Catalog number
    1582-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    AZD-0530
  • Description
    AZD0530 is a dually active inhibitor of c-Src and Bcr-ABL, on bone resorption. AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of focal adhesion kinase (FAK) and paxillin in a dose-dependent manner in a Calu-6 Xenograft model.
  • CAS Number
    379231-04-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₇H₃₂ClN₅O₅
  • Molecular Weight
    542.03
  • Cell Permeable
    Yes
  • Purity
    ≥99% by HPLC
  • Solubilities
    DMSO (~ 200 mg/ml) or EtOH (~ 200 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    A c-Src and Bcr-Abl inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    RT
  • Shelf Life
    24months
  • MDL Number
    MFCD09832698
  • PubChem CID
    10302451
  • SMILES
    CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
  • InChi
    InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
  • InChi Key
    OUKYUETWWIPKQR-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Saracatinib (AZD0530)
  • Alternative name
    Saracatinib (AZD0530)
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