Saracatinib (AZD0530)
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Catalog number1582-25
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PricePlease ask
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Size25 mg
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Alternative_nameAZD-0530
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DescriptionAZD0530 is a dually active inhibitor of c-Src and Bcr-ABL, on bone resorption. AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of focal adhesion kinase (FAK) and paxillin in a dose-dependent manner in a Calu-6 Xenograft model.
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CAS Number379231-04-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₇H₃₂ClN₅O₅
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Molecular Weight542.03
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Cell PermeableYes
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Purity≥99% by HPLC
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SolubilitiesDMSO (~ 200 mg/ml) or EtOH (~ 200 mg/ml)
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HandlingProtect from light and moisture
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Tag LineA c-Src and Bcr-Abl inhibitor
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Storage Condition-20°C
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Shipping ConditionRT
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Shelf Life24months
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MDL NumberMFCD09832698
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PubChem CID10302451
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SMILESCN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
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InChiInChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
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InChi KeyOUKYUETWWIPKQR-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameSaracatinib (AZD0530)
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Alternative nameSaracatinib (AZD0530)
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