anti-NALP7 Antibody

• Catalog number
  5963
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  NALP7 Antibody: NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation. NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. NALP7 inhibits caspase-1-dependent interleukin-1β secretion and is a feedback regulator of interleukin-1β secretion. Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines.
• Gene names
  NALP7 Antibody: HYDM, PAN7, NALP7, NOD12, PYPAF3, CLR19.4, NACHT, LRR and PYD domains-containing protein 7, Nucleotide-binding oligomerization domain protein 12
• Antibodie s label
  unlabelled serum
• Purity
  NALP7 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  NALP7 antibody was made against an 18 amino acid synthetic peptide near the amino terminus of human NALP7.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  NALP7 antibody can be used for detection of NALP7 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  NALP7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  NALP7 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  46049100
• Ncbi nr
  NP_631915
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  199713
• GENE symbol
  NLRP7
• Antigene name
  NLR family, pyrin domain containing 7
• Source
  Homo sapiens
• Protein nr
  Q8WX94
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NALP7  
• Gene symbol
  NLRP7
• Short name
  anti-NALP7 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNALP7 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:22947
• Gene
  NLRP7
• Long gene name
  NLR family pyrin domain containing 7
• Synonyms gene
  • NALP7
• Synonyms gene name
  • NACHT, leucine rich repeat and PYD containing 7
• Synonyms
  • PYPAF3
  • NOD12
  • PAN7
  • CLR19.4
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7
• GenBank acession
  • AF464765
• Locus
  19q13.42
• Discovery year
  2003-10-28
• Entrez gene record
  199713
• Pubmed identfication
  • 12563287
  • 12019269
• RefSeq identity
  • NM_139176
• Classification
  • NLR family
  • Pyrin domain containing
• VEGA ID
  OTTHUMG00000180428
• Locus Specific Databases
  • INFEVERS: The repertory of RMHs sequence variants

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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