Target Alternative Name
Erythropoietin-Alpha, EPO-a, EPO-alpha, Epoetin, EP, mgC138142
Human, Mouse, Rat
KLH conjugated synthetic peptide encompassing a sequence within the center region of human EPO
In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
This antibody is purified by immunogen affinity chromatography
WB: 1:500 - 1:1000
WB: A549; SP2/0; PC12 whole cell lysates
Application And Usages
WB: 1:500 - 1:1000
Human erythropoietin (EPO) is an acidic glycoprotein. It is mainly produced by the kidney. As the primary regulator of the production of red cells, its major functions are to promote erythroid progenitor cells differentiation and to start the synthesis of hemoglobin. EPO acts by binding to a specific erythropoietin receptor (EPOR) on target cells; the red cell precursors in the bone marrow, and induces their transformation into mature erythrocytes. The EPO sensitivity increases with differentiation of immature progenitor cells. EPO may act as a neuron protector against glutamate toxicity. Its neuroprotective activity comes into effect by neutralizing the toxicity of free radicals. EPO is produced in brain after oxidative stress. EPO is upregulated by hypoxia and prevents apoptosis of erythroid progenitors in bone.
For Research Use Only! Not to be used in humans.
The antibody solution should be gently mixed before use.
Western Blot Verified
Dot Blot Verified
Flow Cytometry Verified
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
erythropoietin (Antibody to)
Alternative to gene target
erythropoietin, EP and MVCD2, EPO and IDBG-31941 and ENSG00000130427 and 2056, protein kinase activator activity, Extracellular, Epo and IDBG-205003 and ENSMUSG00000029711 and 13856, EPO and IDBG-640493 and ENSBTAG00000003430 and 280784