EPO Antibody
-
Catalog number6969-100
-
PricePlease ask
-
Size100 µg
-
-
Antibody TargetEPO
-
Target Alternative NameErythropoietin-Alpha, EPO-a, EPO-alpha, Epoetin, EP, mgC138142
-
Antibody TypePolyclonal
-
Species ReactivitiesHuman, Mouse, Rat
-
Immunogen SequenceKLH conjugated synthetic peptide encompassing a sequence within the center region of human EPO
-
AccessionP01588
-
Gene Id2056
-
AppearanceColorless liquid
-
FormLiquid
-
Concentration1 mg/ml
-
FormulationIn 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
-
PurificationThis antibody is purified by immunogen affinity chromatography
-
ApplicationWB: 1:500 - 1:1000
-
Positive ControlWB: A549; SP2/0; PC12 whole cell lysates
-
Application And UsagesWB: 1:500 - 1:1000
-
DescriptionHuman erythropoietin (EPO) is an acidic glycoprotein. It is mainly produced by the kidney. As the primary regulator of the production of red cells, its major functions are to promote erythroid progenitor cells differentiation and to start the synthesis of hemoglobin. EPO acts by binding to a specific erythropoietin receptor (EPOR) on target cells; the red cell precursors in the bone marrow, and induces their transformation into mature erythrocytes. The EPO sensitivity increases with differentiation of immature progenitor cells. EPO may act as a neuron protector against glutamate toxicity. Its neuroprotective activity comes into effect by neutralizing the toxicity of free radicals. EPO is produced in brain after oxidative stress. EPO is upregulated by hypoxia and prevents apoptosis of erythroid progenitors in bone.
-
Storage Condition-20 °C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
UsageFor Research Use Only! Not to be used in humans.
-
HandlingThe antibody solution should be gently mixed before use.
-
Western Blot VerifiedVerified
-
Immunocytochemistry VerifiedNot Verified
-
Immunofluorescence VerifiedNot Verified
-
Immunoprecipitation VerifiedNot Verified
-
ELISA VerifiedNot Verified
-
ChIP VerifiedNot Verified
-
Dot Blot VerifiedNot Verified
-
Flow Cytometry VerifiedNot Verified
-
PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolEPO, TIMP1, EPX
-
Short nameEPO Antibody
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit Ig
-
Alternative nameerythropoietin (antibody to-)
-
Alternative techniqueantibodies
-
Alternative to gene targeterythropoietin, EP and MVCD2, EPO and IDBG-31941 and ENSG00000130427 and 2056, protein kinase activator activity, Extracellular, Epo and IDBG-205003 and ENSMUSG00000029711 and 13856, EPO and IDBG-640493 and ENSBTAG00000003430 and 280784
-
Gene info
-
Identity
-
Gene
-
Long gene nameerythropoietin
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameTIMP metallopeptidase inhibitor 1
-
Synonyms gene
-
Synonyms gene name
- tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
-
Synonyms
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
RefSeq identity
-
Classification
- Tissue inhibitor of metallopeptidases
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameeosinophil peroxidase
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-11-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data