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Alternative_name
1-[3-[3-(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy-3- oxopropyl]disulfanylpropanoyloxy]-2,5-dioxopyrrolidine-3-sulfonic acid; Sulfo-DSP; DTBSSP
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Description
KEY FEATURES & APPLICATIONS: • Water-soluble • Has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends • Contains cleavable, 8-atom (12 Å) spacer arm • The disulfide bond in the spacer arm is cleavable with reducing agents such as DTT, TCEP, etc. • DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins
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CAS Number
81069-02-5
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₁₄H₁₄O₁₄N₂S₄Na₂
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Molecular Weight
608.51
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Cell Permeable
Yes
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Purity
≥80% by NMR
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Solubilities
H₂O (>6 mg/ml)
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Handling
Protect from air and light
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Tag Line
A cleavable homobifunctional protein crosslinking reagent
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Storage Condition
+4 ̊C
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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PubChem CID
123933
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SMILES
CN(OC(CCSSCCC(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)=O)=O)C(CS(=O)(O[Na])=O)=O
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InChi
InChI=1S/C13H18N2O13S4.2Na/c1-14(10(17)7-31(21,22)23)27-11(18)2-4-29-30-5-3-12(19)28-15-9(16)6-8(13(15)20)32(24,25)26;;/h8H,2-7H2,1H3,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2
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InChi Key
LFRKLPYHXPWFCL-UHFFFAOYSA-L
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MSDS Available
Yes