HEY2 Antibody

• Catalog number
  bs-9461R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HEY2 Primary Polyclonal Antibody
• Also known as
  HEY2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HEY2
• Specificity
  This is a highly specific antibody against HEY2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEY2
• Gene ID number
  23493
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  bHLHb32; Cardiovascular helix loop helix factor 1; Cardiovascular helix-loop-helix factor 1; CHF1; Class B basic helix-loop-helix protein 32; GRIDLOCK; GRL; Hairy and enhancer of split related 2; Hairy and enhancer of split-related protein 2; Hairy related transcription factor 2; Hairy-related transcription factor 2; Hairy/enhancer-of-split related with YRPW mot protein 2; hCHF1; HERP; HERP1; HES related repressor protein 1; HES-related repressor protein 2; HESR-2; HESR2; HEY2; HEY2_HUMAN; hHRT2; HRT-2; HRT2; Protein gridlock homolog.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HEY2  
• Gene symbol
  HEY2-AS1, HEY2
• Short name
  Anti-HEY2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HEY2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55652
• Gene
  HEY2-AS1
• Long gene name
  HEY2 antisense RNA 1
• Locus
  6q22.31
• Discovery year
  2021-06-28
• Entrez gene record
  105377986
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:4881
• Gene
  HEY2
• Long gene name
  hes related family bHLH transcription factor with YRPW motif 2
• Synonyms gene name
  • hairy/enhancer-of-split related with YRPW motif 2
  • hes-related family bHLH transcription factor with YRPW motif 2
• Synonyms
  • bHLHb32
  • HERP1
  • HESR2
• GenBank acession
  • AJ249545
• Locus
  6q22.31
• Discovery year
  1999-10-12
• Entrez gene record
  23493
• Pubmed identfication
  • 10415358
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000015512

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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