Bisindolylmaleimide I

  • Catalog number
    1945-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide; GF 109203X; Gö 6850; BIM I
  • Description
    Cell-permeable. A Potent and ATP-competitive protein kinase C (PKC) inhibitor (Ki = 10 nM). Also acts as a potent Glycogen synthase kinase-3 (GSK-3) inhibitor.
  • CAS Number
    133052-90-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₂₄N₄O₂
  • Molecular Weight
    412.49
  • Cell Permeable
    Yes
  • Purity
    ≥98% by NMR
  • Solubilities
    DMSO (~ 10 mg/ml)
  • Handling
    Protect from light and air
  • Tag Line
    A Potent and ATP-competitive protein kinase C (PKC) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00236428
  • PubChem CID
    2396
  • SMILES
    1S/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)
  • InChi
    CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
  • InChi Key
    QMGUOJYZJKLOLH-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Bisindolylmaleimide I
  • Alternative name
    Bisindolylmaleimide I
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