Bisindolylmaleimide I
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Catalog number1945-5
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PricePlease ask
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Size5 mg
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Alternative_name3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide; GF 109203X; Gö 6850; BIM I
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DescriptionCell-permeable. A Potent and ATP-competitive protein kinase C (PKC) inhibitor (Ki = 10 nM). Also acts as a potent Glycogen synthase kinase-3 (GSK-3) inhibitor.
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CAS Number133052-90-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₂₄N₄O₂
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Molecular Weight412.49
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Cell PermeableYes
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Purity≥98% by NMR
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SolubilitiesDMSO (~ 10 mg/ml)
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HandlingProtect from light and air
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Tag LineA Potent and ATP-competitive protein kinase C (PKC) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00236428
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PubChem CID2396
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SMILES1S/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)
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InChiCN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
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InChi KeyQMGUOJYZJKLOLH-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBisindolylmaleimide I
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Alternative nameBisindolylmaleimide I
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