SOX2, phosphorylated (Ser83) (Transcription Factor SOX-2)

• Catalog number
  MBS629057
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [SOX2]
• Products_name_syn
  [Anti -SOX2, phosphorylated (Ser83) (Transcription Factor SOX-2)]
• Other_names
  [SOX2]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human SOX2 when phosphorylated at Ser83.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Gel Shift Assay (GS/EMSA)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  SOX2   phosphorylated   Ser83   Transcription   Factor   SOX-2  
• Gene symbol
  SOX2, SOX2-OT, SOX13, SOX10, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2
• Short name
  SOX2, phosphorylated (Ser83) (Transcription Factor SOX-2)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  SRY (sex determining region Y)-box 2, phosphorylated (Ser83) (Transcription Factor SOX-2)
• Alternative to gene target
  SRY (sex determining region Y)-box 2, ANOP3 and MCOPS3, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, protein heterodimerization activity, nuclei, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383

Gene info

• Identity
  HGNC:11195
• Gene
  SOX2
• Long gene name
  SRY-box transcription factor 2
• Synonyms gene name
  • SRY (sex determining region Y)-box 2
  • SRY-box 2
• GenBank acession
  • BC013923
• Locus
  3q26.33
• Discovery year
  1993-11-30
• Entrez gene record
  6657
• Pubmed identfication
  • 7849401
• RefSeq identity
  • NM_003106
• Classification
  • SRY-box transcription factors
• VEGA ID
  OTTHUMG00000158222
• Locus Specific Databases
  • LOVD
  • LRG_719

Gene info

• Identity
  HGNC:20209
• Gene
  SOX2-OT
• Long gene name
  SOX2 overlapping transcript
• Synonyms gene
  • SOX2OT
• Synonyms gene name
  • SOX2 overlapping transcript (non-protein coding)
• Synonyms
  • DKFZp761J1324
  • NCRNA00043
• Synonyms name
  • non-protein coding RNA 43
• GenBank acession
  • AL157425
  • AK022826
• Locus
  3q26.33
• Discovery year
  2003-07-01
• Entrez gene record
  347689
• Pubmed identfication
  • 12612584
  • 19767420
  • 28960757
• RefSeq identity
  • NR_004053
• Classification
  • Overlapping transcripts
• VEGA ID
  OTTHUMG00000158186

Gene info

• Identity
  HGNC:11192
• Gene
  SOX13
• Long gene name
  SRY-box transcription factor 13
• Synonyms gene name
  • SRY (sex determining region Y)-box 13
  • SRY-box 13
• Synonyms
  • Sox-13
  • ICA12
  • MGC117216
• Synonyms name
  • islet cell antibody 12
  • SRY-related HMG-box gene 13
  • type 1 diabetes autoantigen
• Locus
  1q32.1
• Discovery year
  1998-12-11
• Entrez gene record
  9580
• Pubmed identfication
  • 10198172
• RefSeq identity
  • NM_005686
• Classification
  • SRY-box transcription factors
• VEGA ID
  OTTHUMG00000036050

Gene info

• Identity
  HGNC:11190
• Gene
  SOX10
• Long gene name
  SRY-box transcription factor 10
• Synonyms gene name
  • SRY (sex determining region Y)-box 10
  • SRY-box 10
• Synonyms
  • DOM
  • WS4
  • WS2E
  • SOX-10
• Synonyms name
  • dominant megacolon, mouse, human homolog of
• Locus
  22q13.1
• Discovery year
  1998-01-22
• Entrez gene record
  6663
• Pubmed identfication
  • 9462749
  • 10441344
  • 12944398
• RefSeq identity
  • NM_006941
• Classification
  • SRY-box transcription factors
• VEGA ID
  OTTHUMG00000149913
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • Global Variome shared LOVD
  • LRG_271

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

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