p21,WAF1 (Cip1, Sdi1, Pic1,Wild-type p53-activated Fragment, Tumor Suppressor Protein)
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Catalog numberGEN601539
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PricePlease ask
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Size0.25 ml
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Also known asp21,WAF1
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Other namesp21; Cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1; p21; CDK-interacting protein 1; melanoma differentiation-associated protein; cyclin-dependent kinase inhibitor 1A (P21); CDK-interacting protein 1; Melanoma differentiation-associated protein; p21
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameCdkn1a; Cdkn1a; P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p21Cip1; Cip1; Waf1
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Gene name synonimsCdkn1a; Cdkn1a; P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p21Cip1; Cip1; Waf1
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Other gene namesCdkn1a; Cdkn1a; P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p21Cip1; Cip1; Waf1
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2b
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Clone0.N.487
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human p21, WAF1(Cip1, Sdi1, Pic1, Wild-type p-53-activated fragment, tumor suppressor protein). Species Crossreactivity: Rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein A affinity chromatography.
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Form AppearanceSupplied as a liquid in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide, before the addition of glycerol to 40%.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applicationsWestern Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionKinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
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Gene target
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Gene symbolCDKN1A
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Short namep21 WAF1 (Cip1, Sdi1, Pic1 Wild- p53-activated , Tumor Suppressor Protein)
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IsotypeAntibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
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Alternative nameAnti-p21,WAF1 (Cip1, Sdi1, Pic1,Wild-type p53-activated Fragment, Tumor Suppressor Protein)
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene namecyclin dependent kinase inhibitor 1A
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Synonyms gene
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Synonyms gene name
- cyclin-dependent kinase inhibitor 1A (p21, Cip1)
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-05-24
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Entrez gene record
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data