Anti-LYSINE-SPECIFIC HISTONE DEMETHYLASE (N-TERMINAL)

• Catalog number
  MBS224076
• Price
  Please ask
• Size
  100ug

• Alternative name1
  Anti-RABBIT ANTI LYSINE-SPECIFIC HISTONE DEMETHYLASE (N-TERMINAL)
• Alternative name2
  RABBIT ANTI LYSINE-SPECIFIC HISTONE DEMETHYLASE (N-TERMINAL)
• Alternative name3
  Lapin ANTI LYSINE-SPECIFIC HISTONE DEMETHYLASE (N-TERMINAL)
• Alternative name4
  LYSINE-SPECIFIC HISTONE DEMETHYLASE
• Alternative name5
  N/A
• Other names
  lysine-specific histone demethylase 1A isoform a; Lysine-specific histone demethylase 1A; lysine-specific histone demethylase 1A; lysine (K)-specific demethylase 1; BRAF35-HDAC complex protein BHC110; amine oxidase (flavin containing) domain 2; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; lysine (K)-specific demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  KDM1A; KDM1A; AOF2; KDM1; LSD1; BHC110; AOF2; KDM1; KIAA0601; LSD1
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  Polyclonal IgG
• Clone
  Polyclonal antibody
• Host organism
  Rabbit
• Species reactivity
  Human
• Specificity and cross reactivity
  LYSINE-SPECIFIC HISTONE DEMETHYLASE This item recognises Lysine-specific histone demethylase (LSD1), a ubiquitously expressed nuclear protein belonging to the flavin monoamine oxidase family. _x000D__x000D_Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is an amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues, e.g H3-K4, are associated with active transcription.
• Purification method
  N/A
• Form Appearance
  Purified (Purified IgG - liquid)
• Concentration
  IgG concentration 1.0mg/ml
• Storage and shipping
  Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
• Tested for
  Western Blot (WB)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  LYSINE-SPECIFIC   HISTONE   DEMETHYLASE  
• Gene symbol
  KDM6B, KDM1A, KDM7A
• Short name
  Anti-LYSINE-SPECIFIC HISTONE DEMETHYLASE (N-TERMINAL)
• Technique
  anti-, anti, antibody to, antibodies
• Alternative name
  Antibody toLYSINE-SPECIFIC HISTONE DEMETHYLASE (N-TERMINAL)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29012
• Gene
  KDM6B
• Long gene name
  lysine demethylase 6B
• Synonyms gene
  • JMJD3
• Synonyms gene name
  • jumonji domain containing 3
  • jumonji domain containing 3, histone lysine demethylase
  • lysine (K)-specific demethylase 6B
• Synonyms
  • KIAA0346
• GenBank acession
  • AB002344
• Locus
  17p13.1
• Discovery year
  2004-02-27
• Entrez gene record
  23135
• Pubmed identfication
  • 10662545
  • 9205841
• RefSeq identity
  • NM_001080424
• Classification
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000178021

Gene info

• Identity
  HGNC:29079
• Gene
  KDM1A
• Long gene name
  lysine demethylase 1A
• Synonyms gene
  • AOF2
  • KDM1
• Synonyms gene name
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
• Synonyms
  • KIAA0601
  • BHC110
  • LSD1
• Synonyms name
  • Lysine-specific histone demethylase 1A
• GenBank acession
  • AL031428
• Locus
  1p36.12
• Discovery year
  2004-02-26
• Entrez gene record
  23028
• Pubmed identfication
  • 9628581
  • 12493763
• RefSeq identity
  • NM_015013
• Classification
  • MicroRNA protein coding host genes
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000003220

Gene info

• Identity
  HGNC:22224
• Gene
  KDM7A
• Long gene name
  lysine demethylase 7A
• Synonyms gene
  • JHDM1D
• Synonyms gene name
  • jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
  • lysine (K)-specific demethylase 7A
• Synonyms
  • KIAA1718
• Locus
  7q34
• Discovery year
  2007-03-26
• Entrez gene record
  80853
• Pubmed identfication
  • 20023638
  • 20084082
• RefSeq identity
  • NM_030647
• Classification
  • PHD finger proteins
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000157327

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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