Recombinant Human CD153 / CD30L / TNFSF8 Protein 200µg

• Catalog number
  PKSH030309-200µg
• Price
  Please ask
• Size
  200µg

• Synonym
  CD153;CD30L;CD30LG
• Activity
  NA
• Sequence
  Gln63-Asp234
• Fusion tag
  NA
• Accession
  NP_001235.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞90 % as determined by SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  19.6 kDa
• AP Mol Mass
  19.6 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. CD30L is a type-II membrane glycoprotein expressed on activated T cells, stimulated monocyte-macrophages, granulocytes, eosinophils, and some Burkitt-like lymphoma cell lines. CD30L is capable of transducing signals through CD30 on different CD30+ lymphoma cell lines, and mediates pleiotropic biologic effects including cell proliferation, activation, differentiation, as well as cell death by apoptosis. CD30-CD30 ligand interaction has been suggested to have a pathophysiologic role in malignant lymphomas, particularly Hodgkin disease, large cell anaplastic lymphomas and Burkitt lymphomas, and is also involved in activation and functioning of the T cell-dependent immune response. Thus, CD153 and its receptor CD30 are regarded as therapeutic targets in hematologic malignancies, autoimmune and inflammatory diseases.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD153   CD30L   TNFSF8   Protein   200µg  
• Gene symbol
  TNFSF8
• Short name
  Recombinant CD153 / CD30L / TNFSF8 Protein 200µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens CD153 / CD30L / tumor necrosis factor (ligand) superfamily, member 8 Protein 200µg
• Alternative technique
  rec
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 8, CD153 and CD30L and CD30LG, TNFSF8 and IDBG-82328 and ENSG00000106952 and 944, protein binding, Extracellular, Tnfsf8 and IDBG-155788 and ENSMUSG00000028362 and 21949, BT.44261 and IDBG-638653 and ENSBTAG00000025782 and 574056

Gene info

• Identity
  HGNC:11938
• Gene
  TNFSF8
• Long gene name
  TNF superfamily member 8
• Synonyms gene
  • CD30LG
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 8
• Synonyms
  • CD153
• GenBank acession
  • L09753
• Locus
  9q32-q33.1
• Discovery year
  1993-11-08
• Entrez gene record
  944
• Pubmed identfication
  • 8391931
  • 9349718
• Classification
  • Tumor necrosis factor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000021025

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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