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Jervine for cell activation

Jervine for cell activation is available 2 times from Biovision labs

2357-5 | Jervine for cell activation size: 5 mg | 656.57 USD

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2357-1 | Jervine for cell activation size: 1 mg | 211.65 USD

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Other name (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1­1bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexad­ecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H­-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1­H)-one
Supplied with N/A
Description Cell-permeable. Structurally similar to cyclopamine (Cat. No. 1578). Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Tomatidine (Cat. No. 1893) is a useful negative control.
Category Biochemicals
Molecular formula C₂₇H₃₉NO₃
Is it cell-permeable? Yes
Molecular weight 425.6
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by TLC
Peptide sequence N/A
Is this a salt? No
CAS number 469-59-0
Storage instructions Protect from air and moisture
Maximum time for storage 36 months
Physical appearance White to off-white solid
Reconstitute instructions DMSO (5 mg/ml) or EtOH (10 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetJervine for activation
Short name Jervine for activation
Technique activation
Alternative name Jervine to measure cellular activation
Tissue cell
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