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Products_type
Antibody
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Products_short_name
[TNFRSF11A / RANK]
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Products_name_syn
[Anti-TNFRSF11A / RANK Antibody (aa326-616, clone 9A725) IHC-plus; TNFRSF11A; CD265; CD265 antigen; ODFR; LOH18CR1; OPTB7; OSTS; PDB2; RANK; Receptor activator of NF-KB; TRANCER; FEO; OFE; Human TNFRSF11A; RANK]
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Other_names
[tumor necrosis factor receptor superfamily member 11A isoform 1; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11A; Paget disease of bone 2; receptor activator of NF-KB; osteoclast differentiation factor receptor; receptor activator of nuclear factor-kappa B; loss of heterozygosity, 18, chromosomal region 1; tumor necrosis factor receptor superfamily, member 11a, NFKB activator; Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD_antigen: CD265]
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Products_gene_name
[TNFRSF11A]
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Other_gene_names
[TNFRSF11A; TNFRSF11A; FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1; RANK; ODFR]
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Clonality
Monoclonal
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Clone
[9A725]
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Reactivity
Human, Mouse
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Specificity
A fusion protein containing amino acid residues 326-616 of human RANK was used as immunogen. This antibody recognizes an epitope located between amino acid residues 330-427 of human RANK.
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Purity
Protein G Purified
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Form
PBS, 0.2% gelatin, 0.05% sodium azide.
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Concentration
0.5 mg/ml
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Storage_stability
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Flow Cytometry (FC/FACS)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
TNFRSF11A, ANKFY1
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Short name
Mouse Monoclonal [clone 9A725] (IgG1) TNFRSF11A / RANK
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Technique
Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1, IgG1
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Species
Human, Humans, Mouses
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Alternative name
Mouse monoclonal [clonality 9A725] (IgG1) to H. sapiens tumor necrosis factor receptor superfamily, member 11a, NFKB activator / RANK
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Alternative technique
murine
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 11a, NFKB activator, CD265 and FEO and LOH18CR1 and ODFR and OFE and OPTB7 and OSTS and PDB2 and RANK and TRANCER, TNFRSF11A and IDBG-4279 and ENSG00000141655 and 8792, metal ion binding, Cell surfaces, Tnfrsf11a and IDBG-185529 and ENSMUSG00000026321 and 21934, TNFRSF11A and IDBG-644974 and ENSBTAG00000007569 and 530884
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Clone name
9A725
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