BAY-1436032

• Catalog number
  B1570-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  3-(2-((4-(trifluoromethoxy)phenyl)amino)-1-((1R,5R)-3,3,5-trimethylcyclohexyl)-1H-benzo[d]imidazol-5-yl)propanoic acid
• Description
  BAY-1436032 is a potent and highly selective inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1). BAY 1436032 strongly reduces 2-HG (2-hydroxyglutarate) levels in cells carrying IDH1-R132H, -R132C, -R132G, -R132S and -R132L mutations.
• CAS Number
  1803274-65-8
• Structure Available
  Yes
• Molecular Formula
  C₂₆H₃₀F₃N₃O₃
• Molecular Weight
  489.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent and highly selective inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1)
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• SMILES
  O=C(O)CCC1=CC=C2N([C@H]3CC(C)(C)C[C@@H](C)C3)C(NC4=CC=C(OC(F)(F)F)C=C4)=NC2=C1
• InChi
  InChI=1S/C26H30F3N3O3/c1-16-12-19(15-25(2,3)14-16)32-22-10-4-17(5-11-23(33)34)13-21(22)31-24(32)30-18-6-8-20(9-7-18)35-26(27,28)29/h4,6-10,13,16,19H,5,11-12,14-15H2,1-3H3,(H,30,31)(H,33,34)/t16-,19+/m0/s1
• InChi Key
  RNMAUIMMNAHKQR-QFBILLFUSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BAY-1436032  
• Short name
  BAY-1436032
• Alternative name
  BAY-1436032

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