Recombinant Rat OLR1 / LOX1 Protein (His tag) 50µg
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Catalog number
PKSR030274-50µg
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Price
Please ask
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Size
50µg
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Synonym
OLR1;Lox1;Oldlr1
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Activity
NA
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Sequence
Leu60-Gln364
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Fusion tag
N-His
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Accession
O70156
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ExpressedHost
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 90 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
37.9 kDa
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AP Mol Mass
43-47 KDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is inducted by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions.
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Conjugation
histidine
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
OLR1
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Short name
Recombinant OLR1 / LOX1 Protein (His tag) 50µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
Rat
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Label
His
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Species
Rat, Rats
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Alternative name
Rec. Rat oxidized low density lipoprotein (lectin-like) receptor 1 / LOX1 Protein (histidine detection labelled) 50µg
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Alternative technique
rec
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Alternative to gene target
oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A and LOX1 and LOXIN and SCARE1 and SLOX1, OLR1 and IDBG-18612 and ENSG00000173391 and 4973, carbohydrate binding, nuclei, Olr1 and IDBG-192019 and ENSMUSG00000030162 and 108078, OLR1 and IDBG-639562 and ENSBTAG00000004547 and 281368
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Gene info
MeSH Data
Product images
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