Adipophilin, human, recombinant

• Catalog number
  4597-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Adipose differentiation-related protein, ADRP, ADFP, MGC10598.
• Alternative_names
  Adipose differentiation-related protein, ADRP, ADFP, MGC10598, Perilipin-2
• Description
  A major constituent of the globule surface
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Molecular Weight
  49.0 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from 0.5 mg/ml solution containing 20mM Tris pH 7.5, and 20 mM NaCl,
• Reconstitution Instructions
  Add de-ionized H₂O to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Background Information
  Adipophilin is a 49 kDa protein that belongs to the PAT family (perilipin, adipophilin, TIP47, S3-12 and OXPAT), which comprises proteins involved in the coating of lipid droplets. ADFP is expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes. ADFP expression has a role in clear cell renal carcinoma differentiation. Most recently, it has been discovered that patients with kidney cancers had high levels of ADFP in their urine, suggesting that ADFP could be an excellent marker for kidney cancer.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Adipophilin  
• Gene symbol
  PLIN2
• Short name
  Adipophilin, , recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Adipophilin, H. sapiens, Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:248
• Gene
  PLIN2
• Long gene name
  perilipin 2
• Synonyms gene
  • ADFP
• Synonyms gene name
  • adipose differentiation-related protein
• Synonyms
  • ADRP
• Synonyms name
  • adipophilin
• GenBank acession
  • X97324
• Locus
  9p22.1
• Discovery year
  1992-02-07
• Entrez gene record
  123
• Pubmed identfication
  • 9003395
  • 19638644
• RefSeq identity
  • NM_001122
• Classification
  • Perilipins
• VEGA ID
  OTTHUMG00000019624

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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