anti-FAK (Ab 576 / 577) Antibody

• Catalog number
  79-433
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
• Gene names
  FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, JTK2, TKF, FADK 1, PTK2
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of total FAK protein.
• Antigen
  FAK (Ab-576/577) antibody was made against a peptide sequence around aa.574~578/575~579 (T-Y-Y-K-A) derived from Human FAK.
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  27886593
• Ncbi nr
  NP_005598.3
• KDa
  125 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  5747
• GENE symbol
  PTK2
• Antigene name
  protein tyrosine kinase 2
• Source
  Homo sapiens
• Protein nr
  Q05397
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FAK   576   577  
• Gene symbol
  PTK2
• Short name
  anti-FAK (Ab 576 / 577) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toFAK (Antibody 576 / 577) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9611
• Gene
  PTK2
• Long gene name
  protein tyrosine kinase 2
• Synonyms gene name
  • PTK2 protein tyrosine kinase 2
• Synonyms
  • FAK
  • FADK
  • FAK1
  • PPP1R71
• Synonyms name
  • protein phosphatase 1, regulatory subunit 71
• GenBank acession
  • L13616
• Locus
  8q24.3
• Discovery year
  1992-10-02
• Entrez gene record
  5747
• Pubmed identfication
  • 8422239
• RefSeq identity
  • NM_005607
• Classification
  • Protein phosphatase 1 regulatory subunits
  • FERM domain containing
  • PTK2 family tyrosine kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000067438

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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