ML-354

• Catalog number
  9415-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol
• Description
  ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).
• CAS Number
  89159-60-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₄N2O₃
• Molecular Weight
  282.39
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective PAR4 antagonist
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  752812
• PubChem CID Link
• SMILES
  CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1CO)C3=CC=CC=C3
• InChi
  InChI=1S/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3
• InChi Key
  GNJUKVGDCUKDLF-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  354  
• Gene symbol
  RNA5SP354, RN7SL354P, LINC00354
• Short name
  -354
• Alternative name
  milliliter-354

Gene info

• Identity
  HGNC:43254
• Gene
  RNA5SP354
• Long gene name
  RNA, 5S ribosomal pseudogene 354
• Synonyms gene
  • RN5S354
• Synonyms gene name
  • RNA, 5S ribosomal 354
• Locus
  12p11.23
• Discovery year
  2012-01-30
• Entrez gene record
  100873614

Gene info

• Identity
  HGNC:46370
• Gene
  RN7SL354P
• Long gene name
  RNA, 7SL, cytoplasmic 354, pseudogene
• Locus
  15q21.2
• Discovery year
  2013-04-02
• Entrez gene record
  106481838

Gene info

• Identity
  HGNC:42672
• Gene
  LINC00354
• Long gene name
  long intergenic non-protein coding RNA 354
• Locus
  13q34
• Discovery year
  2011-08-15
• Entrez gene record
  101928616
• Classification
  • Long intergenic non-protein coding RNAs
• VEGA ID
  OTTHUMG00000017361

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