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Antibody category
Monoclonal Antibody
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Antibody s description
Monoclonal Mouse Antibody against Human Aggrecan Neoepitope N-terminal Sequence ARGSVIL
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Raised in
Mouse
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Research area of interest
Diseases associated with ACAN include Osteochondritis Dissecans, Short Stature, And Early-Onset Osteoarthritis and Spondyloepimetaphyseal Dysplasia, Aggrecan Type. Among its related pathways are Diseases associated with O-glycosylation of proteins and Integrin Pathway.
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Package form
liquid
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Clonality
Monoclonal
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Antigen
N-terminal sequence ARGSVIL of human aggrecan neoepitope.
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Reacts with
Human
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Immunogen
See the data sheet or contact us
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Contents
20 mM Na-phosphate, pH 7.5, 150 mM NaCl
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Purity
>95%
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Tested applications
• ELISA • Western-Blotting with TMB/ECL-Detection, suggested dilution 1 : 2000
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Other names
Monoclonal Mouse Antibody against Human Aggrecan Neoepitope N-terminal Sequence ARGSVIL
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Crossreactivity
no crossreactivty
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Antibody specificity
reacts with the N-terminal sequence ARGSVIL of aggrecan fragments produced by proteolysis at the aggrecanase site within the interglobular domain of aggrecan (aggrecan-IGD). It does not react to a significant extent with the sequence ARGSVIL contained within uncleaved polypeptide chains
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Purification
Protein A purified
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PubMed citations
See the data sheet
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UniProt number
P16112
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Storage conditions
- 70°C
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Technical datasheet
Contact us to receive the datasheet
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Shipping condition
dry ice
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Warnings
For Research Use only.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Test
biotez supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Latin name
Mus musculus