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Phorbol-12-myristate 13-acetate (PMA)

Phorbol-12-myristate 13-acetate (PMA) is available 1 time from Biovision labs

1544-5 | Phorbol-12-myristate 13-acetate (PMA) size: 5 mg | 249.62 USD

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Alternative_name PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Description This is the most commonly used phorbol ester. It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues and is a very potent mouse skin tumor promoter. Inhibits apoptosis induced by the Fas antigen, but induced apoptosis in HL-60 promyelocytic leukemia cells
CAS Number 16561-29-8
Structure Available? Yes
Salt Form No
Molecular Formula C₃₆H₅₆O₈
Molecular Weight 616.83
Cell-Permeable? Yes
Purity >99%
Solubilities DMSO or EtOH
Handling Protect from light
Tag Line A PKC activator
Storage Condition -20°C
Shipping Condition gel pack
Shelf Life 12 months
MDL Number MFCD00036736
PubChem CID 27924
SMILES CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
InChi InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34-,35-,36-/m1/s1
InChi Key PHEDXBVPIONUQT-RGYGYFBISA-N
MSDS Available Yes
Gene targetPhorbol-12-myristate 13-acetate PMA
Short name Phorbol-12-myristate 13-acetate (PMA)
Alternative name Phorbol-12-myristate 13-acetate (PMA)
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