Rofecoxib

  • Catalog number
    B1982-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    4-(4-(methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one; MK-966; MK966
  • Description
    Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent cyclooxygenase-2 (COX-2) inhibitor. It displays 1,000-fold selectivity for COX-2 over that of COX-1 (IC₅₀s = 26 nM and > 50 µM in human osteosarcoma cells).
  • CAS Number
    162011-90-7 
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₇H₁₄O₄S 
  • Molecular Weight
    314.36
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A non-steroidal anti-inflammatory drug (NSAID) and a potent cyclooxygenase-2 (COX-2) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    5090
  • SMILES
    CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3
  • InChi
    InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
  • InChi Key
    RZJQGNCSTQAWON-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Rofecoxib
  • Alternative name
    Rofecoxib
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