Rofecoxib
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Catalog numberB1982-50
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PricePlease ask
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Size50 mg
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Alternative_name4-(4-(methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one; MK-966; MK966
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DescriptionRofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent cyclooxygenase-2 (COX-2) inhibitor. It displays 1,000-fold selectivity for COX-2 over that of COX-1 (IC₅₀s = 26 nM and > 50 µM in human osteosarcoma cells).
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CAS Number162011-90-7
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₁₄O₄S
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Molecular Weight314.36
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA non-steroidal anti-inflammatory drug (NSAID) and a potent cyclooxygenase-2 (COX-2) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID5090
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SMILESCS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3
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InChiInChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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InChi KeyRZJQGNCSTQAWON-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameRofecoxib
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Alternative nameRofecoxib
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